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Immediate relief. No upset stomach, no numbing of fingers, just sweet relief. I took .06 at onset and .06 eight hours later, pain gone in about 20 hours.

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COLCRYS is contraindicated in patients with renal or hepatic impairment who are currently prescribed P-gp inhibitors or strong inhibitors of CYP3A4.

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No stomach upset as I take Zegerid daily.

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